Package: kangar00 Type: Package Title: Kernel Approaches for Nonlinear Genetic Association Regression Version: 1.4.2 Date: 2024-05-09 Authors@R: c( person("Juliane", "Manitz", role = c("aut","cre"), email = "r@manitz.org"), person("Benjamin", "Hofner", role= "aut"), person("Stefanie", "Friedrichs", role = "aut"), person("Patricia", "Burger", role = "aut"), person("Ngoc Thuy", "Ha", role="aut"), person("Saskia", "Freytag", role="ctb"), person("Heike", "Bickeboeller", role="ctb")) URL: https://kangar00.manitz.org/ BugReports: https://github.com/jmanitz/kangar00/issues Description: Methods to extract information on pathways, genes and various single-nucleotid polymorphisms (SNPs) from online databases. It provides functions for data preparation and evaluation of genetic influence on a binary outcome using the logistic kernel machine test (LKMT). Three different kernel functions are offered to analyze genotype information in this variance component test: A linear kernel, a size-adjusted kernel and a network-based kernel). License: GPL-2 Encoding: UTF-8 Collate: 'pathway.r' 'GWASdata.r' 'data.R' 'get_network_matrix.r' 'kernel.r' 'lkmt.r' Depends: R (>= 3.5.0) Imports: methods, bigmemory, sqldf, CompQuadForm, data.table, lattice, igraph LazyData: true Suggests: biomaRt, KEGGgraph, testthat NeedsCompilation: no RoxygenNote: 7.3.1 Config/pak/sysreqs: libglpk-dev libxml2-dev Repository: https://jmanitz.r-universe.dev Date/Publication: 2024-09-09 16:43:42 UTC RemoteUrl: https://github.com/jmanitz/kangar00 RemoteRef: HEAD RemoteSha: a91c39f643e9f8c9d073478f3694efe42f65b357 Packaged: 2026-10-01 09:41:13 UTC; root Author: Juliane Manitz [aut, cre], Benjamin Hofner [aut], Stefanie Friedrichs [aut], Patricia Burger [aut], Ngoc Thuy Ha [aut], Saskia Freytag [ctb], Heike Bickeboeller [ctb] Maintainer: Juliane Manitz